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Haemodynamic stability during general anaesthesia for intra‐ocular surgery: the effect of topical oxybuprocaine
Author(s) -
Lytle J.,
Thomas N. F.
Publication year - 1992
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1992.tb02339.x
Subject(s) - medicine , anesthesia , general anaesthesia , hemodynamics , enflurane , reflex , surgery , halothane
Summary Local anaesthesia is frequently used in combination with light general anaesthesia to reduce the reflex responses to surgical stimulation. This combination has not previously been evaluated for intra‐ocular surgery. During cataract extraction under general anaesthesia, the effect of topical anaesthesia with oxybuprocaine 0.4% on the pressor response was compared with normal saline in a control group. The simple technique of instilling local anaesthetic drops into the conjunctival sac blocked the pain pathway sufficiently to prevent the pressor response to surgical stimulation (p < 0.001). Higher inspired concentrations of enflurane were required in the control group to achieve and maintain haemodynamic stability (p < 0.001).