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Malignant hyperthermia
Author(s) -
HARRISON G. G.,
ISAACS H.
Publication year - 1992
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1992.tb01956.x
Subject(s) - medicine , malignant hyperthermia , hyperthermia , general anaesthesia , anesthesia
Summary This paper reports previously unpublished accounts of the deaths in 1915 and 1919 of two members of the same family during general anaesthesia. The deaths were subsequently ascribed to a‘hereditary susceptibility to chloroform. Contemporary evidence is presented which suggests that these deaths were among the very earliest examples of malignant hyperthermia to be described.