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Effect of fentanyl on the circulatory responses to orotracheal fibreoptic intubation
Author(s) -
SMITH J. E.,
KING M. J.,
YANNY H. F.,
POTTINGER K. A.,
POMIRSKA M. B.
Publication year - 1992
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1992.tb01946.x
Subject(s) - fentanyl , medicine , anesthesia , premedication , intubation , orotracheal intubation , isoflurane , tracheal intubation , heart rate , elective surgery , blood pressure
Summary The effectiveness of fentanyl in attenuating the pressor and heart rate response to orotracheal fibreoptic intubation under general anaesthesia was assessed in 60 healthy patients undergoing elective surgery. Patients were randomly assigned to receive either fibreoptic intubation with or without fentanyl 6μg.kg −1 or traditional Macintosh intubation with fentanyl 6μg.kg −1 . A standardised general anaesthetic was administered which included temazepam premedication, thiopentone, atracurium, oxygen, nitrous oxide and isoflurane. The pressor response to fibreoptic intubation was suppressed in those patients who received fentanyl and was similar to that seen in the Macintosh‐fentanyl group of patients. The heart rate response to fibreoptic intubation was also significantly reduced in the patients who received fentanyl, but, in contrast, was still significantly greater than that in the Macintosh‐fentanyi group. Fentanyl 6μg.kg −1 appears to have a useful place in attenuating the cardiovascular effects of fibreoptic intubation under general anaesthesia.