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Comparison of extradural and intravenous diamorphine as a supplement to extradural bupivacaine
Author(s) -
LEE A.,
McKEOWN D.,
BROCKWAY M.,
BANNISTER J.,
WILDSMITH J. A. W.
Publication year - 1991
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1991.tb11680.x
Subject(s) - medicine , bupivacaine , anesthesia , surgery , abdominal surgery , local anesthetic
Summary The influence of route of administration (extradural as compared with intravenous) of diamorphine 0.5 mg/hour as a supplement to extradural bupivacaine (0.125% at 15 ml/hour) was investigated in two groups of 20 patients who underwent major abdominal gynaecological surgery. Significantly more patients in the intravenous group withdrew because of inadequate analgesia (p < 0.05). Those in the extradural group were significantly more drowsy throughout the study (p < 0.01), but no major side effects were encountered.