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Reversible renal failure following opioid administration
Author(s) -
HILL S. A.,
QUINN K.,
SHELLY M. P.,
PARK G. R.
Publication year - 1991
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1991.tb09852.x
Subject(s) - medicine , administration (probate law) , opioid , anesthesia , intensive care medicine , law , political science , receptor
Summary A patient who received intravenous papaveretum during and after operation developed anuria and biochemical evidence of impaired renal function in the first 6 hours after surgery. Administration of naloxone 0.4 mg was associated with a sustained improvement in urine output. Mean arterial pressure did not change significantly. The impairment of renal function may have been related to high plasma concentrations of codeine, one of the constituents of papaveretum.