Premium
Epidural bupivacaine dilution for labour
Author(s) -
NOBLE H. A.,
ENEVER G. R.,
THOMAS T. A.
Publication year - 1991
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1991.tb09653.x
Subject(s) - bupivacaine , medicine , anesthesia , fentanyl , local anesthetic , surgery
Summary We have compared the effects of three epidural infusions in a randomised, double‐blind study of 56 primigravid mothers in labour. An initial dose of bupivacaine 0.5% 8 ml was followed by infusion of either bupivacaine 0.125%, 0.062% or 0.031%. All solutions contained fentanyl 0.0002% and were run at 7.5 ml/hour. Women receiving the most dilute solution had significantly less analgesia (p < 0.001) for the first 4 hours of the study, but pain scores were then similar for the three groups. No obvious benefit was gained by using very dilute bupivacaine.