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Topical glyceryl trinitrate and eutectic mixture of local anaesthetics in children A randomised controlled trial on choice of site and ease of venous cannulation
Author(s) -
TeillolFoo W. L. M.,
Kassab J. Y.
Publication year - 1991
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1991.tb09610.x
Subject(s) - medicine , placebo , anesthesia , eutectic system , randomized controlled trial , surgery , materials science , alternative medicine , alloy , pathology , composite material
Summary One hundred and four children aged between 1 and 11 years were studied in a double‐blind randomised controlled trial of glyceryl trinitrate ointment versus placebo, when used in addition to standard eutectic mixture of local anaesthetics cream. Each child received glyceryl trinitrate ointment on one hand and placebo on the other, and thus acted as his/her own control. A group of 30 children who received only the eutectic mixture on both hands (60 measurements) was also studied. The choice of site and ease of cannulation was scored. Skin colour and venous dilatation under the eutectic mixture were scored on a visual analogue scale. The addition of topical glyceryl trinitrate ointment to the standard eutectic mixture positively affected venous dilatation (p < G.01), choice of cannulation site (p < 0.001), and ease of cannulation (p < 0.001) of topical anaesthetic‐treated skin.