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Ketamine, midazolam and vecuronium infusion Anaesthesia for Down's syndrome and congenital heart disease
Author(s) -
RILEY D. P.,
McBRIDE L. J.
Publication year - 1991
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1991.tb09356.x
Subject(s) - midazolam , medicine , ketamine , anesthesia , saline , heart disease , mechanical ventilation , oxygenation , cardiology , sedation
Summary A ketamine, midazolam and vecuronium infusion was used for total intravenous anesthesia in a patient with Down's syndrome, a ventricular septal defect and pulmonary hypertension. A mixture of ketamine 200 mg, midazolam 5 mg and vecuronium 12 mg in 50 ml of normal saline was infused at 0.5 ml/kg/hour. This simple technique and ventilation with 100% oxygen maintained tissue oxygenation and cardiovascular stability.