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Modification of pain on injection of propofol—a comparison between lignocaine and procaine
Author(s) -
Nicol M. E.,
Moriarty J.,
Edwards J.,
Robbie D. S.,
A'Hern R. P.
Publication year - 1991
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1991.tb09323.x
Subject(s) - medicine , procaine , propofol , anesthesia , lidocaine , pain relief
Summary Pain on injection of propofol was assessed in a controlled, randomised study of 273 patients. They received either lignocaine 10 mg, procaine 10 mg or isotonic saline 0.5 ml, 15 seconds before the injection of propofol into a vein on the back of the hand. The incidence of pain on injection in the'control group (51%) was comparable with other studies. Lignocaine and procaine both significantly reduced the pain (35% and 34% respectively, p < 0.05) but there was no statistical difference between these two groups.