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Management of low cardiac output syndrome after cardiac surgery using enoximone
Author(s) -
WHITE D. A.,
LATIMER R. D.,
ODURO A.
Publication year - 1990
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1990.tb14783.x
Subject(s) - enoximone , medicine , inotrope , cardiac output , cardiology , cardiac surgery , vascular resistance , anesthesia , perfusion , phosphodiesterase inhibitor , vasodilation , hemodynamics
Summary This case report describes the use of enoximone, a potent phosphodiesterase F‐IV inhibitor with inotropic and vasodilator actions, to treat low output syndrome after cardiac surgery. The reduced cardiac output was unresponsive to a combination of inotropic drugs and intra‐aortic balloon counterpulsation was contraindicated. Cardiac output was increased dramatically by enoximone, but systemic vascular resistance and perfusion pressure remained low until the addition of metaraminol.