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pH‐adjustment and discomfort caused by the intradermal injection of lignocaine
Author(s) -
Martin A. J.
Publication year - 1990
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1990.tb14636.x
Subject(s) - medicine , sodium bicarbonate , local anaesthetic , anesthesia , lidocaine , local anesthetic , bicarbonate , local anesthesia , surgery , chemistry
Summary One hundred adult day‐case patients who required intravenous access had cannulae inserted using local anaesthesia with 1% lignocaine, 1% lignocaine with adrenaline or the corresponding pH‐adjusted solutions. The local anaesthetic solutions were modified by the addition of 1 ml 8.4% sodium bicarbonate to 10 ml lignocaine. Pain scores at different stages of cannulation were noted and showed a significant reduction after use of pH‐adjusted solutions (p < 0.02 for the plain lignocaine, and < 0.001 for the lignocaine with adrenaline). Modification of the pH of lignocaine solutions by the addition of sodium bicarbonate is a simple method significantly to reduce the discomfort caused by the infiltration of the local anaesthetic.