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A clinical study into the possible intrinsic bradycardic activity of vecuronium
Author(s) -
COZANITIS D. A.,
ERKOLA O.
Publication year - 1989
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1989.tb13585.x
Subject(s) - medicine , enflurane , anesthesia , vecuronium bromide , heart rate , saline , blood pressure , halothane
Summary Forty female patients received a standardised anaesthetic technique with thiopentone sodium and enflurane. Half of the patients received, under double‐blind conditions, either physiological saline or glycopyrronium before induction of anaesthesia; 10 minutes after induction of anaesthesia, all patients received vecuronium 0.1 mg/kg. A further 10 patients received neither glycopyrronium nor vecuronium. The results show that vecuronium per se does not produce a decrease in heart rate.