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Inheritance of low plasma cholinesterase activity in two families with a history of suxamethonium sensitivity
Author(s) -
WHITTAKER M.,
BERRY M.,
BRITTEN J. J.
Publication year - 1989
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1989.tb11373.x
Subject(s) - cholinesterase , inheritance (genetic algorithm) , medicine , family history , genotype , sensitivity (control systems) , genetics , gene , biology , electronic engineering , engineering
Summary An hypothesis advanced in 1970 concerning family inheritance of low enzymic activities of plasma cholinesterase has been substantiated. The recognition of three E 1 k E 1 S genotypes is reported in this family after investigation of a new generation. A second family with similar genetic characteristics is described.