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Hyperosmolality due to antacid treatment
Author(s) -
FARAJ J. H.
Publication year - 1989
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1989.tb09146.x
Subject(s) - antacid , medicine , dehydration , tonicity , coma (optics) , fluid intake , magnesium , anesthesia , renal physiology , intensive care medicine , renal function , biochemistry , chemistry , physics , materials science , optics , metallurgy
Summary Magnesium trisilicate mixture is an antacid used commonly in our Intensive Care Unit in the prevention and treatment of stress ulcers. In this case the administration of large doses over a period of time led to the development of massive hyperosmolality, cerebral dehydration and coma. Management with hypotonic fluid resulted in complete recovery.