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Intranasal sufentanil for pre‐operative sedation
Author(s) -
VERCAUTEREN M.,
BOECKX E.,
HANEGREEFS G.,
NOORDUIN H.,
BUSSCHE G.
Publication year - 1988
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1988.tb08970.x
Subject(s) - sufentanil , medicine , sedation , anesthesia , narcotic , nose , nasal administration , saline , surgery , pharmacology
Summary Sufentanil, a short‐acting and potent narcotic agent, was studied as a premedicant administered by the nasal route. A total dose of 5 μg appeared to be too low, while either 10 or 20 μg was very effective in producing sedation. Side effects were minor. There appeared to be no differences between nose drops and spray. In a further study, sufentanil nose drops were compared with saline (0.9% in a double‐blind fashion. Sedation of rapid onset but of limited duration was observed in the majority of patients who received sufentanil.