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Clinical relevance of the B 12 /N 2 O interaction A report of a seminar
Author(s) -
NUNN J. F.
Publication year - 1988
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1988.tb06696.x
Subject(s) - medicine , relevance (law) , nitrous oxide , clinical significance , intensive care medicine , anesthesia , pathology , political science , law
Summary The interaction of nitrous oxide and vitamin B 12 and its implications are not the exclusive territory of any one discipline. The initial discovery was by a chemist but it is of obvious relevance to anaesthetists and intensivists; some complications are neurological others haematological. The interaction provides an extremely important research tool as the first easily available B 12 ‐deficient animal model. Finally there are implications for exposure to contaminated atmospheres in hospitals and in industry.