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Alkalinised bupivacaine and adrenaline for epidural Caesarean section
Author(s) -
TACKLEY R. M.,
COE A. J.
Publication year - 1988
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1988.tb05698.x
Subject(s) - medicine , bupivacaine , caesarean section , anesthesia , apgar score , local anesthetic , lower segment caesarean section , surgery , pregnancy , fetus , biology , genetics
Summary Twenty‐four mothers received either 0.5% bupivacaine (group 1, n = 14), or alkalinised 0.5% bupivacaine and 1 in 200 000 adrenaline (group 2, n = 10), as an epidural local anaesthetic for elective lower segment Caesarean section in a randomised, double blind study. The two groups were prepared for surgery according to an identical technique. Onset of analgesia to pinprick was significantly faster in group 2 (p < 0.02). Group 1 required additional analgesia during surgery significantly more often than those in group 2 (p = 0.04). Significantly more patients in group 2 were ready for surgery by the time limit for the study (45 minutes, p = 0.002). Onset of motor blockade was significantly faster in group 2 (p = 0.01). There were no significant differences between the two groups with regard to duration of surgery, or Apgar scores at 1 and 5 minutes. Alkalinised 0.5% bupivacaine and adrenaline was superior to 0.5% bupivacaine for epidural Caesarean section.