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Lignocaine 2% with adrenaline for epidural Caesarean section
Author(s) -
NORTON A. C.,
DAVIS A. G.,
SPICER R. J.
Publication year - 1988
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1988.tb05597.x
Subject(s) - medicine , bupivacaine , caesarean section , anesthesia , blockade , dermatome , significant difference , local anesthetic , apgar score , pregnancy , fetus , receptor , biology , genetics
Summary A randomised double blind controlled trial of freshly prepared 2% lignocaine with 1/200 000 adrenaline and 0.5% plain bupivacaine was conducted on 60 women undergoing elective Caesarean section. The use of the former enabled epidural blockade to above the T 6 dermatome to be established in a significantly shorter time than with bupivacaine (p < 0.005). The quality of sensory blockade and incidence of complications was similar in the two groups. The solutions were of similar potency as measured by the volume required per segment blocked. Motor blockade was more intense with 2% lignocaine with adrenaline (p < 0.03). More neonates had moderately depressed Apgar scores (5–7) at one minute in the lignocaine group but this difference was not statistically significant, and there was no difference in the distribution of Apgar scores at 3 minutes. Lignocaine with 1/200 000 adrenaline is a useful alternative to 0.5% plain bupivacaine when it is desired to establish rapidly epidural blockade for Caesarean section.