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Isoflurane as an alternative to halothane for Caesarean section
Author(s) -
GHALY R. G.,
FLYNN R. J.,
MOORE J.
Publication year - 1988
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1988.tb05412.x
Subject(s) - medicine , isoflurane , halothane , caesarean section , anesthesia , section (typography) , pregnancy , biology , genetics , advertising , business
Summary Two series of 25 patients who underwent elective Caesarean section with general anaesthesia were given either 0.75% isoflurane or 0.5% halothane as supplements to 50% nitrous oxide in oxygen used for maintenance. The potent inhalational agent was given for the entire operative period and no case of intra‐operative dreaming or awareness was reported. The infusion dose of suxamethonium was significantly less with isoflurane, 50 μg/kg/minute (SD 17), as compared to halothane, 64 μg/kg/minute (SD 24) (p < 0.02). Recovery from anaesthesia was more rapid with isoflurane. The surgeon's assessment of uterine relaxation and bleeding using a visual analogue score indicated that this was significantly less with isoflurane. Infant well‐being as judged by Apgar score and cord blood gas analysis, showed little difference between the two inhalational agents.