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Suxamethonium in myasthenia gravis
Author(s) -
WAINWRIGHT A. P.,
BRODRICK P. M.
Publication year - 1987
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1987.tb05365.x
Subject(s) - medicine , myasthenia gravis , anesthesia , block (permutation group theory) , mathematics , geometry
Summary The effects of suxamethonium 1.0 and 0.5 mg/kg were studied in myasthenie patients. Resistance was not encountered at the 1.0 mg/kg dose but was seen at the lower dose. A non‐depolarising type of block developed in patients in both groups. However, recovery from the non‐depolarising block was not prolongea beyond the requirements of surgery. The neurophysiological basis for, and clinical implications of these findings are discussed.