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Comparison of trichloroethylene and enflurane as adjuncts to nitrous oxide and relaxant anaesthesia
Author(s) -
Rice A. S. C.,
Reynolds F.
Publication year - 1987
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1987.tb05284.x
Subject(s) - enflurane , medicine , anesthesia , nitrous oxide , trichloroethylene , nausea , vomiting , fentanyl , halothane , muscle relaxant , postoperative nausea and vomiting , chemistry , environmental chemistry
Summary Forty women who underwent gynaecological surgery were randomly allocated to receive trichloroethylene. enflurane, or enflurane plus fentanyl as adjuncts to nitrous oxide/relaxant anaesthesia with controlled ventilation. No serious cardiac dysrhythmias were seen in any group. Each patient was observed postoperatively' for 4 hours by a nurse blind to the technique used, and questioned at 24 hours by a similarly blinded anaesthetist. Recovery after trichloroethylene was not significantly prolonged although postoperative analgesia by visual analogue was better, opiate analgesia was required less frequently and there was less nausea and vomiting than in either of the enflurane groups. We argue for the continued use of trichloroethylene by this technique, because it costs one hundred times less than enflurane and because of the potential morbidity of the postoperative opiate dosage required after enflurane.