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Hepatotoxicity and death following two enflurane anaesthetics
Author(s) -
PAULL J. D.,
FORTUNE D. W.
Publication year - 1987
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1987.tb05227.x
Subject(s) - enflurane , medicine , anesthesia , intensive care medicine , halothane
Summary A 67‐year‐old woman died with massive fatty change in the liver 41 hours after her second enflurane anaesthetic in 28 days. The clinical features of five previously reported similar deaths are summarised. Possible mechanisms of the hepatotoxicity are reviewed briefly.