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The respiratory depressant effects of nalbuphine and papaveretum as intramuscular premedication
Author(s) -
RUTTHR G. G. R.,
AVELING W.,
TUSIEWICZ K.
Publication year - 1987
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1987.tb05223.x
Subject(s) - premedication , nalbuphine , medicine , anesthesia , depression (economics) , respiratory system , significant difference , opioid , receptor , economics , macroeconomics
Summary Forty‐four patients scheduled for routine gynaecological surgery through a Pfannenstiel incision were given either nalbuphine or papaveretum as premedication, with hyoseine. Respiratory depression was measured by carbon dioxide rebreathing before and one hour after premedication. Both combinations produced significant respiratory depression as measured by the rebreathing test but no significant difference could be shown between the drugs in this respect.