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Comparison of epidural fentanyl with sufentanil
Author(s) -
MADEJ T. H.,
STRUNIN L.
Publication year - 1987
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1987.tb05220.x
Subject(s) - sufentanil , medicine , fentanyl , anesthesia , bolus (digestion) , surgery
Summary Duration of analgesia and side effects following single bolus doses of epidural fentanyl (100 μg) or sufentanil (10, 20, 30 or 50 μg) were studied in 50 patients who underwent Caesarean section under epidural anaesthesia. Fewer patients experienced pain peroperatively in the fentanyl group than in a joint group of those given sufentanil 20 or 30 μg (p < 0.05). The combined fentanyl and sufentanil 50 μg groups had fewer patients in pain than the sufentanil 10 μg group at 3 hours after injection (p < 0.05). Patients given fentanyl also had a longer pain‐free interval than those who received sufentanil 10 μg (p < 0.02). The sufentanil 50 μg group had more patients asleep than the 10 μg group and also had more patients with pruritus than the 10 μg or 30 μg groups (p < 0.02). The patients given sufentanil 30 and 50 μg had more emetic sequelae than those who received sufentanil 10 and 20 μg or fentanyl 100 μg (p < 0.05). There was no detectable excretion of drug into breast milk and no significant respiratory depression at the time of first postoperative analgesia in the patients who received fentanyl or 30 μg or less of sufentanil.