Premium
Intravenous feeding with medium chain triglycerides. Effect on blood gases and the complement system in critically ill patients
Author(s) -
Ball M. J.,
Sear J. W.
Publication year - 1986
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1986.tb13232.x
Subject(s) - medicine , critically ill , parenteral nutrition , complement system , adverse effect , white blood cell , intensive care medicine , anesthesia , immunology , antibody
Summary Critically ill patients are usually in a catabolic state and may require total parenteral nutrition; this often includes lipid emulsions. Any adverse effects of constituents on pulmonary function, white cell function or the haemocoagulation system could have disastrous consequences in such patients. We have investigated the effects of a new intravenous lipid preparation containing medium chain triglyceriks, which, in severely ill malnourished patients are theoretically a preferable energy source to conventional drug chain triglycerides. In a pilot study 17 critically ill patients whose lungs were artificially ventilated were given this lipid emulsion; no adverse eflects were observed. Arterial oxygen and carbon dioxide tensions, ratio of inspired oxygen fractional concentration to arterial oxygen tension. platelet and white cell counts all remained constant and the complement system was not activated.