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Epidural buprenorphine for postoperative analgesia. A controlled comparison with epidural morphine.
Author(s) -
Wolff J.,
Carl P.,
Crawford M.E.
Publication year - 1986
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1986.tb12710.x
Subject(s) - medicine , buprenorphine , morphine , anesthesia , opioid , surgery , receptor
Summary In a double‐blind controlled study. epidural buprenorphine 0.3 mg was compared with 4 mg of epidural morphine for postoperative pain relief the first 24 hours after major orthopaedic surgery. The degree of analgesia was equal and sarisfactory in both groups. Duration of action was 620 minutes with buprenorphine and 580 minutes with morphine, which was not significantly deferent. The only serious side effects were recorded in the morphine group, with two patients complaining of pruritus and give of urinary retention. In conclusion, epidural buprenorphine did not offer any advantages in preference to morphine for postoperative pain relief following orthopaedic surgery.