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Anaphylactoid reactions during anaesthesia
Author(s) -
GALLETLY D. C.,
TREUREN B. C.
Publication year - 1985
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1985.tb10785.x
Subject(s) - medicine , anaphylactoid reactions , atopy , anesthesia , incidence (geometry) , allergy , anaphylaxis , immunology , physics , optics
Summary Sixty one patients who had suffered intra‐operative anaphylactoid reactions were studied. Intradermal testing identified the causative agent in 84% of cases and, in 75% of these, muscle relaxants were responsible. Predisposing factors in patients sensitive to muscle relaxants were: female sex, previous allergy and atopy. The incidence of previous exposure was considerably higher than that reported in the literature. Pancuronium is suggested to be the least likely currently available agent to provoke a major anaphylactoid reaction.