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Assessment and modification of pain on induction with propofol (Diprivan)
Author(s) -
McCulloch M.J.,
Lees N.W.
Publication year - 1985
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1985.tb10615.x
Subject(s) - medicine , propofol , anesthesia , incidence (geometry) , cardiorespiratory fitness , forearm , dorsum , surgery , physical therapy , physics , optics , anatomy
Summary Assessment of pain on injection of the emulsified formulation of di‐isopropylphenol (propofol, ‘Diprivan’) was undertaken in 120 unpremedicated patients and comparison made with thiopentone. A high incidence of pain (37.5%) was found using dorsal hand veins, but use of forearm veins showed only a 2.5% incidence of pain. The use of intravenous lignocaine immediately before propofol injection only partially reduced the incidence of pain using dorsal hand veins (17.5%). A degree of cardiorespiratory depression accompanied induction but the incidence of other side effects was low.