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Neuromuscular transmission and its blockade
Author(s) -
JONES R. M.
Publication year - 1985
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1985.tb10551.x
Subject(s) - neuromuscular transmission , neuromuscular blockade , medicine , blockade , neuromuscular junction , anesthesia , neuromuscular monitoring , neuroscience , receptor , biology
Summary The role of two recently introduced muscle relaxants—atracurium and vecuronium—in contemporary anaesthetic practice is assessed. Recent advances in the physiology of neuromuscular transmission, particularly the roles of calcium and calmodulin, are reviewed, and new ideas concerning the reversal and monitoring of neuromuscular blockade are discussed.