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Ischaemia following selfadministered intra‐arterial injection of methylphenidate and diamorphine
Author(s) -
CORSER G.,
MASEY S.,
JACOB G.,
KERNOFF P.,
BROWNE D.
Publication year - 1985
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1985.tb10503.x
Subject(s) - medicine , anesthesia , urokinase , heroin , methylphenidate , ischemia , heparin , artery , vasodilation , surgery , drug , pharmacology , cardiology , psychiatry , attention deficit hyperactivity disorder
Summary A patient presented with a painful, oedematous, cyanosed hand having injected a solution of diamorphine and methylphenidate into his radial artery. Treatment was started with heparin and vasodilators. Benefit from this was limited and a course of intra‐arterial urokinase was instituted. This gave almost total resolution of the injury. The mechanisms producing ischaemia following intra‐arterial injection of drugs of abuse and possible treatment are discussed.