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Intracranial pressure after phenoperidine
Author(s) -
GRUMMITT R. M.,
GOAT V. A.
Publication year - 1984
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1984.tb07363.x
Subject(s) - medicine , sedative , sedation , intracranial pressure , intensive care unit , anesthesia , controlled ventilation , mechanical ventilation , intensive care medicine
Summary The problem of sedating patients requiring prolonged controlled ventilation has recently received considerable attention. 1‐3 Various therapeutic regimes are available and there appears to be a general move away from the use of muscle relaxants towards sedative drugs. Phenoperidine is a popular agent for this purpose. One survey from a district general hospital reported that 66% of their ventilated intensive therapy unit patients received phenoperidine, either alone or as part of a sedation regime. 4 However, enthusiasm for its use must be tempered by recent reports of cardiovascular collapse following its administration. 5,6 We wish to report a case of intracranial hypertension following the use of phenoperidine in a ventilated patient with a severe head injury.