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Acid‐base control during hypothermia Acid‐base contrnl in children during hypothermia without temperature correction of pH and P CO 2
Author(s) -
MATTHEWS A. J.,
STEAD A. L.,
ABBOTT T. R.
Publication year - 1984
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1984.tb06472.x
Subject(s) - medicine , hypothermia , anesthesia , cardiopulmonary bypass , perfusion , oxygenator , acid–base reaction , acid–base homeostasis , base (topology) , surgery , cardiology , chemistry , organic chemistry , mathematical analysis , mathematics
Summary In 28 children undergoing cardiopulmonary bypass with deep hypothermia for open heart surgery, an attempt was made to maintain pH at 7.4 not corrected for temperature by varying the CO 2 concentration supplied to the oxygenator so that the PaCO 2 was 5.33 kPa, not corrected for temperature. One to two percent CO 2 gave satisfactory results. Five percent CO 2 had previously been given. No adverse clinical side effects were noted, and the acid‐base status remainpd stable for 24 hours in 16 patients. There are strong theoretical reasons for maintaining a pH of 7.4, uncorrected for temperature, during hypothermia and a clinical impression was gained of better myocardial function and improved systemic and cerebral perfusion.