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The effect of 50% nitrous oxide in oxygen on lower oesophageal sphincter tone
Author(s) -
BrockUtne John G.,
Downing John W.
Publication year - 1983
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1983.tb10465.x
Subject(s) - nitrous oxide , medicine , anesthesia , reflex , gastric content , sedative , respiratory tract , sphincter , respiratory system , muscle tone , stomach , surgery , psychiatry
Summary The effect of 50% nitrous oxide on the lower oesophageal sphincter was studied in eight healthy volunteers. No effect on the sphincter lone was noted in these subjects. The importance of this finding is discussed in relation to the depressant effects of nitrous oxide and other anaesthetic or sedative drugs on the reflex protective mechanisms safeguarding the respiratory tract and lungs from aspiration of acid gastric content and other foreign matter.

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