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High dose buprenorphine for postoperative analgesia
Author(s) -
Budd Keith
Publication year - 1981
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1981.tb08867.x
Subject(s) - medicine , buprenorphine , anesthesia , analgesic , depression (economics) , surgery , opioid , receptor , economics , macroeconomics
Summary Buprenorphine was given intravenously to produce analgesia in the immediate postoperative period, the dose being titrated against the response of each patient in order to obtain complete freedom from pain. In 50 patients following lower segment Caesarean section under general anaesthesia, buprenorphine in the dose range 0.4–7.0 mg was found to be a potent, long lasting and safe analgesic. Serial blood gas estimations performed on ten of the patients confkmed the clinically observed lack of respiratory depression.