Premium
Initial experience with Minaxolone
Author(s) -
Punchihewa V. G.,
Morgan M.,
Lumley Jean,
Whitwam J. G.
Publication year - 1980
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1980.tb03805.x
Subject(s) - medicine , fentanyl , nausea , anesthesia , incidence (geometry) , nitrous oxide , muscle tone , surgery , physics , psychiatry , optics
Summary Minaxolone has been used to induce anaesthesia, and in incremental doses to supplement nitrous oxide, in 100 patients undergoing minor surgical procedures. Half the patients received a small dose of fentanyl before induction. Minaxolone proved to be a satisfactory induction agent. The commonest complications were an increase in muscle tone and imoluntary muscle movements, which in some patients occurred in the recovery period: their incidence was reduced by fentanyl. There was a notably low incidence of nausea and romiting.