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Plasma cholinesterase variants and the anaesthetist
Author(s) -
WHITTAKER MARY
Publication year - 1980
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1980.tb03800.x
Subject(s) - medicine , cholinesterase , genetic variants , butyrylcholinesterase , enzyme , gene , anesthesia , genetics , acetylcholinesterase , biochemistry , aché , genotype , biology
Summary Biochemical properties of plasma cholinesterase of significance to the anaesthetist are reviewed. The role of the genetic variants of the enzyme in suxamethonium sensitivity and hyperthermia are discussed with emphasis on the pregnant patient. Altered gene frequencies of the enzyme variants in some mental disorders is commented upon.