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Ketamine sequelae
Author(s) -
LILBURN J.K.,
DUNDEE J.W.,
NAIR S.G.,
FEE J.P.H.,
JOHNSTON H.M.L.
Publication year - 1978
Publication title -
anaesthesia
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1978.tb12412.x
Subject(s) - medicine , ketamine , anesthesia
The ability of a number of drugs to abolish the emergence delirium and unpleasant dreams which follow anaesthesia induced with 2 mg/kg ketamine was studied. These included three benzodiazepines, droperidol and 'neurolept' combinations and four commonly-used premedicants. When given intravenously 10 min before induction of anaesthesia flunitrazepam and lorazepam gave best results. In a subsequent study, these two benzodiazepines and diazepam were given intravenously 30-40 min before induction of anaesthesia. There was no doubt that 4 mg lorazepam gave the greatest protection and is worthy of further study in this respect.