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Lysosomal enzyme release during cardiopulmonary bypass
Author(s) -
GNANADURAI T.V.,
BRANTHWAITE M.A.,
COLBECK J.F.,
WELMAN E.
Publication year - 1977
Publication title -
anaesthesia
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1977.tb10074.x
Subject(s) - medicine
Lysosomal enzyme release occurs during cardiopulmonary bypass in man but the tissues from which these enzymes originate have not been identified. The activity of N-acetyl beta-glucosaminidase in plasma increases to a degree which is proportional to the duration of bypass and this enzyme may therefore be a better marker than beta-glucuronidase of tissue damage caused by cardiopulmonary bypass, as distinct from tissue damage solely to the operative procedure.