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Ethnic variation, epidemiological factors and quality of life impairment associated with dyspepsia in urban Malaysia
Author(s) -
MAHADEVA S.,
YADAV H.,
RAMPAL S.,
EVERETT S. M.,
GOH K.L.
Publication year - 2010
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/j.1365-2036.2010.04270.x
Subject(s) - medicine , ethnic group , malay , epidemiology , logistic regression , population , demography , quality of life (healthcare) , kuala lumpur , cross sectional study , risk factor , traditional medicine , gerontology , environmental health , pathology , linguistics , philosophy , nursing , marketing , sociology , anthropology , business
Aliment Pharmacol Ther 31 , 1141–1151 Summary Background The role of ethnicity in the development of dyspepsia remains uncertain. Aims To examine the epidemiology of dyspepsia in a multi‐ethnic Asian population and its impact on health‐related quality of life (HRQOL). Methods A cross‐sectional survey was conducted in a representative urban population in Kuala Lumpur, Malaysia. Results A total of 2039 adults (mean ± s.d. age: 40.5 ± 11.8 years, males 44.2%, ethnicity: Malays 45.3%, Chinese 38.0% and Indians 13.1%, tertiary education level 62%, professional employment 47.7% and median monthly income USD 850.00) were interviewed. Dyspepsia was prevalent in 496 (24.3%) adults. Independent predictors for dyspepsia, explored by logistic regression, were identified as: Malay (OR 2.17, 95% CI = 1.57–2.99) and Indian (OR 1.59, 95% CI = 1.03–2.45) ethnicity, heavy chilli intake (OR 2.35, 95% CI = 1.15–4.80), use of regular analgesia (OR 3.51, 95% CI = 2.54–4.87) and chronic illness (OR 1.67, 95% CI = 1.22–2.28). HRQOL was assessed with the EQ‐5D and significantly lower scores were noted in dyspeptics compared with healthy controls (0.85 ± 0.17 vs. 0.95 ± 0.12, P < 0.0001). Conclusion Ethnicity, in addition to recognized epidemiological factors, is a risk factor for dyspepsia in an urban multi‐racial Asian population.