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Future indications for terlipressin therapy
Author(s) -
Lebrec D.
Publication year - 2004
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/j.1365-2036.2004.02116.x
Subject(s) - terlipressin , medicine , hepatorenal syndrome , liver transplantation , vasopressin , paracentesis , resuscitation , vasoconstrictor agents , shock (circulatory) , intensive care medicine , transplantation , anesthesia , ascites , blood pressure
Summary Vasoconstrictor agents such as terlipressin (Glypressin ® ) have been shown to have beneficial effects in the treatment of hepatorenal syndrome (HRS), in terms of improving renal function and subsequent survival rates. Patients with HRS have also been shown to have improved survival after liver transplantation if they receive terlipressin treatment prior to transplantation. In addition, studies show that terlipressin may have beneficial effects in treating other indications, including paracentesis‐induced circulatory dysfunction and endotoxic shock. A positive effect has also been demonstrated with vasopressin in cardiopulmonary resuscitation.