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Rationale and proposed algorithms for symptom‐based proton pump inhibitor therapy for gastro‐oesophageal reflux disease
Author(s) -
Bytzer P.,
Blum A. L.
Publication year - 2004
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/j.1365-2036.2004.02093.x
Subject(s) - medicine , reflux , gastro , proton pump inhibitor , disease , intensive care medicine , on demand , epidemiology , algorithm , gastroenterology , computer science , multimedia
Summary Gastro‐oesophageal reflux disease and non‐erosive reflux disease are chronic, highly prevalent conditions requiring long‐term treatment that is both effective and practical. On‐demand therapy with a proton pump inhibitor may meet that need. It is becoming a mainstay of long‐term treatment because it reduces the risk of over‐ and under‐treatment, is cost‐effective and user friendly. Epidemiological and clinical observations speak also in its favour. However, for the anticipated benefits of on‐demand therapy to accrue in clinical practice, on‐demand treatment algorithms are required. These algorithms must specify the initial evaluation and treatment of candidates, and follow‐up protocols for an on‐demand strategy. Our group has developed such algorithms, which are presented here.