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Effect of treatment with Liu‐Jun‐Zi‐Tang (TJ‐43) on gastric emptying and gastrointestinal symptoms in dyspeptic patients
Author(s) -
TATSUTA M.,
IISHI H.
Publication year - 1993
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/j.1365-2036.1993.tb00120.x
Subject(s) - gastric emptying , medicine , gastroenterology , placebo , acetaminophen , stomach , anesthesia , pathology , alternative medicine
SUMMARY The effects of treatment with the Chinese herbal medicine Liu‐Jun‐Zi‐Tang (TJ‐43) on gastric emptying and gastrointestinal symptoms were investigated in 42 patients with chronic idiopathic dyspepsia. By random allocation, 22 patients received oral treatment with 2.5 g TJ‐43 three times daily, and 20 patients received placebo. Gastric emptying was measured by the acetaminophen absorption method. After 7 days of treatment, gastric emptying was significantly accelerated and gastrointestinal symptoms were significantly reduced in patients treated with TJ‐43. Placebo treatment produced no significant effects. These findings indicate that TJ‐43 had a prokinetic action on gastric emptying and that it was useful in treating chronic dyspepsia.