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Ileo‐caecal ulceration associated with the use of diclofenac slow release
Author(s) -
HUDSON N.,
WILKINSON M.J.,
SWANNELL A. J.,
STEELE R. J.,
HAWKEY C. J.
Publication year - 1993
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/j.1365-2036.1993.tb00090.x
Subject(s) - medicine , ileal diseases , laparotomy , diclofenac , ileum , colonoscopy , abdominal pain , surgery , gastroenterology , iliac fossa , endoscopy , anesthesia , colorectal cancer , cancer
SUMMARY A 38‐year‐old man with seropositive arthropathy on long‐standing treatment with diclofenac slow release presented with abdominal pain, diarrhoea and anaemia. Upper gastrointestinal endoscopy and barium series were unremarkable. Five months later he presented with a right iliac fossa mass. Investigations revealed discrete ulceration in the terminal ileum and caecum confirmed at laparotomy. Other possible causes of intestinal ulceration were excluded suggesting a diagnosis of non‐steroidal anti‐inflammatory drug associated intestinal ulceration.