Open AccessRecent progress in the development of RNA interference for plant parasitic nematodes
Author(s) -
LILLEY CATHERINE J.,
BAKHETIA MANJULA,
CHARLTON WAYNE L.,
URWIN PETER E.
Publication year - 2007
Publication title -
molecular plant pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 103
eISSN - 1364-3703
pISSN - 1464-6722
DOI - 10.1111/j.1364-3703.2007.00422.x
Subject(s) - rna interference , biology , rna silencing , gene silencing , caenorhabditis elegans , gene , trans acting sirna , nematode , rna , function (biology) , genetics , computational biology , ecology
SUMMARY RNA interference (RNAi), first described for Caenorhabditis elegans , has emerged as a powerful gene silencing tool for investigating gene function in a range of organisms. Recent studies have described its application to plant parasitic nematodes. Genes expressed in a range of cell types are silenced when preparasitic juvenile nematodes take up double‐stranded (ds)RNA that elicits a systemic RNAi response. Important developments over the last year have shown that in planta expression of a dsRNA targeting a nematode gene can successfully induce silencing in parasitizing nematodes. When the targeted gene has an essential function, a resistance effect is observed paving the way for the potential use of RNAi technology to control plant parasitic nematodes.