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Overcoming opioid blockade from depot naltrexone (Prodetoxon ® )
Author(s) -
Kruptisky E. M.,
Burakov A. M.,
Tsoy M. V.,
Egorova V. Y.,
Slavina T. Y.,
Grinenko A. Y.,
Zvartau E. E.,
Woody G. E.
Publication year - 2007
Publication title -
addiction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.424
H-Index - 193
eISSN - 1360-0443
pISSN - 0965-2140
DOI - 10.1111/j.1360-0443.2007.01817.x
Subject(s) - naltrexone , blockade , detoxification (alternative medicine) , opioid , heroin , medicine , addiction , pharmacology , anesthesia , psychiatry , drug , alternative medicine , receptor , pathology
Aim To describe a situation in which an opioid‐dependent patient overcame naltrexone blockade. Design, case report, setting Addiction treatment center in St Petersburg, Russia. Participant Patient with naltrexone implant. Intervention Detoxification. Measurements Clinical observations. Conclusions It is possible, but very difficult, to overcome naltrexone blockade by using large doses of heroin.