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NMR T 1 Relaxation Time of the Brain During Alcohol Withdrawal and its Lack of Relationship with Symptom Severity
Author(s) -
MANDER A. J.,
YOUNG A.,
CHICK J. D.,
RIDGWAY J.,
BEST J. J. K.
Publication year - 1989
Publication title -
british journal of addiction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.424
H-Index - 193
eISSN - 1360-0443
pISSN - 0952-0481
DOI - 10.1111/j.1360-0443.1989.tb03483.x
Subject(s) - abstinence , detoxification (alternative medicine) , alcohol dependence , relaxation (psychology) , negative correlation , chronic alcoholic , psychology , withdrawal syndrome , medicine , alcohol , anesthesia , psychiatry , pathology , chemistry , biochemistry , alternative medicine
Summary A significant fall in brain T 1 relaxation time, consistent with a reduction in brain water of approximately 0.3%, occurred in 19 chronic alcoholic patients admitted for detoxification. There was no correlation between T 1 and the severity of withdrawal symptoms and hence no evidence that changes in brain water levels contributed to the abstinence syndrome.