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Lephetamine Abuse and Dependence: clinical effects and withdrawal syndrome
Author(s) -
JANIRI L.,
MANNELLI P.,
PIRRONGELLI C.,
LO MONACO M.,
TEMPESTA E.
Publication year - 1989
Publication title -
british journal of addiction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.424
H-Index - 193
eISSN - 1360-0443
pISSN - 0952-0481
DOI - 10.1111/j.1360-0443.1989.tb00555.x
Subject(s) - abuse liability , withdrawal syndrome , medicine , analgesic , physical dependence , psychiatry , psychology , anesthesia , morphine , drug
Summary Lephetamine (L‐SPA) is a compound with central analgesic and anti‐inflammatory action, recently reported to be abused in Italy. In this study, cases of L‐SPA abuse were recorded. The survey included 15 patients who were assessed for effects caused by using L‐SPA and induced by withdrawal. Moreover L‐SPA was administered to 15 volunteers. L‐SPA displayed effects partly similar to opiates and its withdrawal caused both subjective and objective symptoms. It is concluded that L‐SPA exhibits abuse liability and dependence potential of a certain degree.