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Corpus Callosal Thickness in Alcoholics
Author(s) -
HARPER CLIVE G.,
KRIL JILLIAN J.
Publication year - 1988
Publication title -
british journal of addiction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.424
H-Index - 193
eISSN - 1360-0443
pISSN - 0952-0481
DOI - 10.1111/j.1360-0443.1988.tb02577.x
Subject(s) - corpus callosum , white matter , coronal plane , pathological , psychology , audiology , medicine , anatomy , magnetic resonance imaging , pathology , neuroscience , radiology
Summary The coronal thickness of the corpus callosum in alcoholics and age‐ and sex‐matched controls was measured in a postmortem study. The alcoholics were found to have a significantly (p <0.001) reduced corpus callosal thickness (3.19 mm) when compared to the controls (4.02 mm). This adds weight to the previous pathological finding of reduced white matter volume in alcoholics, which presumably correlates with brain shrinkage seen on CT scans. A significant linear relationship exists between age and the corpus callosal thickness in controls and the white matter volume and corpus callosal thickness in alcoholics.