Open AccessNon‐viral vectors for cancer therapy
Author(s) -
Kaneda Yasufumi,
Tabata Yasuhiko
Publication year - 2006
Publication title -
cancer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 141
eISSN - 1349-7006
pISSN - 1347-9032
DOI - 10.1111/j.1349-7006.2006.00189.x
Subject(s) - genetic enhancement , viral vector , cancer , vector (molecular biology) , cancer therapy , gene transfer , viral therapy , cancer treatment , medicine , virology , gene , biology , covid-19 , pathology , disease , genetics , infectious disease (medical specialty) , recombinant dna
Cancers are diverse and often resistant to therapeutic strategies. Gene therapy has yet to meet the promise of a breakthrough in cancer therapy. There are several barriers to overcome in cancer gene therapy. One of the biggest challenges is the design of appropriate vectors. Numerous viral and non‐viral methods for gene transfer have been developed for human gene therapy, but both viral and non‐viral vectors have limitations and advantages. In this review article, recent improvements in the development of non‐viral vectors for delivering gene therapy for the treatment of cancer will be discussed. ( Cancer Sci 2006; 97: 348 –354)