Open AccessA Case‐Control Study on Risk Factors for Uterine Endometrial Cancer in Japan
Author(s) -
Inoue Masaki,
Okayama Akira,
Fujita Masami,
Enomoto Takayuki,
Tanizawa Osamu,
Ueshima Hirotsugu
Publication year - 1994
Publication title -
japanese journal of cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 141
eISSN - 1349-7006
pISSN - 0910-5050
DOI - 10.1111/j.1349-7006.1994.tb02365.x
Subject(s) - odds ratio , endometrial cancer , medicine , gynecology , case control study , obstetrics , parity (physics) , incidence (geometry) , risk factor , cancer , physics , particle physics , optics
A case control study of 143 Japanese women with uterine endometrial cancer and 143 individually age‐matched controls was conducted to assess the risk factors for endometrial cancers in Japan. Among the characteristics studied, the following factors were significantly greater in the cases than in the controls: nulliparity (odds ratio for parity 1–3 and ≥4 versus nullipara are 0.40 and 0.02, respectively), obesity (odds ratio: 2.73), hypertension (odds ratio: 2.4), diabetes mellitus (odds ratio: 6.30), and a personal medical history of cancer (odds ratio: 3.06). The present study showed that Japanese women have the same risk factors for endometrial cancer as those reported in Western countries. The recent increase in the incidence of endometrial cancer in Japan may be largely attributed to the decrease in parity.